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KMID : 0043319880110030169
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Archives of Pharmacal Research
1988 Volume.11 No. 3 p.169 ~ p.174
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Synthesis of Novel 4-Substituted Phenazone Derivatives as Potential Antibacterial and Antineoplastic Agents
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Girges MM
Abou El Zahab MM/Hanna MA
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Abstract
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A new series of substituted phenazone derivatives has been prepared through a series of reactions that are illustrated in Scheme I. The antibacterial and antineoplastic activities of the prepared compounds were evaluated. While none of the synthesized products showed marked antibacterial activity, all of them possessed a significant antitumor effect.
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